A Carrier at Risk

A Carrier at Risk PDF Author: Mariano Sciaroni
Publisher: Latin America@War
ISBN: 9781911628705
Category : Falkland Islands War, 1982
Languages : en
Pages : 0

Book Description
The naval warfare of the last few decades appears dominated by operations of fast missile craft and a wide diversity of other minor vessels in so-called 'littoral warfare'. As so often, the reality is entirely different. Submarine and anti-submarine warfare remain one of most sophisticated forms of armed conflicts to this day. Unsurprisingly, consi

Assessing Genetic Risks

Assessing Genetic Risks PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309047986
Category : Medical
Languages : en
Pages : 353

Book Description
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.

The Carriers

The Carriers PDF Author: Anne Skomorowsky
Publisher: Columbia University Press
ISBN: 0231552289
Category : Medical
Languages : en
Pages : 118

Book Description
A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation but also experience related conditions themselves. In such cases, carriers can have tremors, infertility, and psychiatric disorders that complicate raising children with fragile X syndrome—and all too often, they suffer in silence. The Carriers investigates this common but still little-known genetic condition and its life-altering consequences. Anne Skomorowsky reveals how this disorder afflicts families across generations, telling the stories of the mothers and grandparents of fragile X patients and considering how genes interact with family dynamics. She interweaves the personal narratives and family histories of the people affected by fragile X disorders with clear and accessible explanations of the science behind them. Skomorowsky unpacks the latest research on the fragile X mutation and explores the history of its discovery. She highlights the roles of women as carriers, caregivers, and researchers who have made astonishing scientific breakthroughs over the last three decades. The Carriers is an essential book for fragile X families, including those just learning they are carriers, and for all readers interested in the complexities of heredity, the ethical dilemmas of genetic medicine, and the relationship between genes and personality.

Introduction to Risk Calculation in Genetic Counseling

Introduction to Risk Calculation in Genetic Counseling PDF Author: Ian D. Young
Publisher: Oxford University Press, USA
ISBN: 0195305272
Category : Mathematics
Languages : en
Pages : 252

Book Description
In third edition of this clear, reader-friendly guide, the author addresses the challenge of calculations in genetic counseling and demonstrates how risk can be estimated for inherited disorders using a basic knowledge of the laws of probability and their application to clinical problems. The text employs a wealth of clearly explained examples and "key points" in order to guide the reader to an accurate assessment of the risk of genetic disease.

Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases PDF Author: Hans D. Ochs
Publisher:
ISBN: 019514774X
Category : Medical
Languages : en
Pages : 745

Book Description
The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

Carrier Battles

Carrier Battles PDF Author: Douglas V Smith
Publisher: Naval Institute Press
ISBN: 1612514421
Category : History
Languages : en
Pages : 396

Book Description
A longtime professor at the Naval War College who once directed strategic and long-range planning for the Navy and Marine Corps in Europe considers the transformation of the U.S. Navy from a defensive-minded coastal defense force into an offensive risk-taking navy in the very early stages of World War II. Noting that none of the navy’s most significant World War II leaders were commissioned before the Spanish-American War and none participated in any important offensive operations in World War I, Douglas Smith examines the premise that education, rather than experience in battle, accounts for that transformation. In this book, Smith evaluates his premise by focusing on the five carrier battles of the second world war to determine the extent to which the inter-war education of the major operational commanders translated into their decision processes, and the extent to which their interaction during their educational experiences transformed them from risk-adverse to risk-accepting in their operational concepts. His book will interest students of the Pacific War, naval aviation, education, and leadership.

Individual Differences and the "high-risk" Commercial Driver

Individual Differences and the Author: Ronald R. Knipling
Publisher: Transportation Research Board
ISBN: 0309088100
Category : Bus drivers
Languages : en
Pages : 94

Book Description
TRB's Commercial Truck and Bus Safety Synthesis Program (CTBSSP) Synthesis 4: Individual Differences and the "High-Risk" Commercial Driver explores individual differences among commercial drivers, particularly as these differences relate to the "high-risk" commercial driver. The synthesis identifies factors relating to commercial vehicle crash risk and assesses ways that the high-risk driver can be targeted by various safety programs and practices, at both fleet- and industry-wide levels.

Advanced Topics in Forensic DNA Typing: Interpretation

Advanced Topics in Forensic DNA Typing: Interpretation PDF Author: John M. Butler
Publisher: Academic Press
ISBN: 012405854X
Category : Social Science
Languages : en
Pages : 609

Book Description
Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. - Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence - Worked mixture examples illustrate the impact of different statistical approaches for reporting results - Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011

Emergency Response Guidebook

Emergency Response Guidebook PDF Author: U.S. Department of Transportation
Publisher: Simon and Schuster
ISBN: 1626363765
Category : House & Home
Languages : en
Pages : 352

Book Description
Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.

The Genetics of Cancer

The Genetics of Cancer PDF Author: B.A. Ponder
Publisher: Springer Science & Business Media
ISBN: 9401106770
Category : Medical
Languages : en
Pages : 222

Book Description
It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
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