Molecular Population Genetics

Molecular Population Genetics PDF Author: Matthew William Hahn
Publisher: Sinauer Associates, Incorporated
ISBN: 9780878939657
Category : Molecular genetics
Languages : en
Pages : 334

Book Description
Published by Sinauer Associates, an imprint of Oxford University Press. Provides descriptions of the methods and tools used in molecular population genetics, which has combined advances in molecular biology and genomics with mathematical and empirical findings to uncover the history of natural selection and demographic shifts in many organisms.

A Primer of Molecular Population Genetics

A Primer of Molecular Population Genetics PDF Author: Asher D. Cutter
Publisher:
ISBN: 0198838948
Category : Science
Languages : en
Pages : 266

Book Description
What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

Population Genetics, Molecular Evolution, and the Neutral Theory

Population Genetics, Molecular Evolution, and the Neutral Theory PDF Author: Motoo Kimura
Publisher: University of Chicago Press
ISBN: 9780226435633
Category : Science
Languages : en
Pages : 736

Book Description
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.

Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory PDF Author: Alan R. Templeton
Publisher: John Wiley & Sons
ISBN: 0470047216
Category : Science
Languages : en
Pages : 720

Book Description
The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Molecular Evolutionary Genetics

Molecular Evolutionary Genetics PDF Author: Masatoshi Nei
Publisher: Columbia University Press
ISBN: 9780231063210
Category : Computers
Languages : en
Pages : 526

Book Description
-- "The Scientist"

The Causes of Molecular Evolution

The Causes of Molecular Evolution PDF Author: John H. Gillespie
Publisher: Oxford University Press
ISBN: 0195357744
Category : Science
Languages : en
Pages : 351

Book Description
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.

Molecular Evolution and Population Genetics for Marine Biologists

Molecular Evolution and Population Genetics for Marine Biologists PDF Author: Yuri Kartavtsev
Publisher: CRC Press
ISBN: 9781498701600
Category : Science
Languages : en
Pages : 0

Book Description
Research in modern experimental and theoretical population genetics has been strengthened by advances in molecular techniques for the analysis of genetic variability. The evolutionary relationships of organisms may be investigated by comparing DNA sequences. This book covers chapters on population genetics, DNA polymorphism, genetic homeostasis, and biochemical genetics, plus a chapter on phylogenetic tree construction. In addition, each chapter contains training materials with numerical examples.

Population Genetics

Population Genetics PDF Author: Matthew B. Hamilton
Publisher: John Wiley & Sons
ISBN: 1444362453
Category : Science
Languages : en
Pages : 658

Book Description
This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Evolutionary Genetics

Evolutionary Genetics PDF Author: R. S. Singh
Publisher: Cambridge University Press
ISBN: 9780521571234
Category : Medical
Languages : en
Pages : 738

Book Description
This book brings out the central role of evolutionary genetics in all aspects of its connection to evolutionary biology.

Genetics of Populations

Genetics of Populations PDF Author: Philip Hedrick
Publisher: Jones & Bartlett Learning
ISBN: 0763757373
Category : Science
Languages : en
Pages : 690

Book Description
The Fourth Edition of Genetics of Populations is the most current, comprehensive, and accessible introduction to the field for advanced undergraduate and graduate students, and researchers in genetics, evolution, conservation, and related fields. In the past several years, interest in the application of population genetics principles to new molecular data has increased greatly, and Dr. Hedrick's new edition exemplifies his commitment to keeping pace with this dynamic area of study. Reorganized to allow students to focus more sharply on key material, the Fourth Edition integrates coverage of theoretical issues with a clear presentation of experimental population genetics and empirical data. Drawing examples from both recent and classic studies, and using a variety of organisms to illustrate the vast developments of population genetics, this text provides students and researchers with the most comprehensive resource in the field.
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