The Binding

The Binding PDF Author: Bridget Collins
Publisher: HarperCollins UK
ISBN: 0008272131
Category : Fiction
Languages : en
Pages : 457

Book Description
LOSE YOURSELF IN THE BREAKOUT SENSATION OF THE YEAR SHORTLISTED FOR WATERSTONES BOOK OF THE YEAR 2019 ‘Brilliant’ Joanna Cannon ‘Spellbinding’ Guardian ‘Magic’ Erin Kelly ‘Immersive’ Sunday Times ‘Gorgeous' Stella Duffy ‘Astounding’ Anna Mazzola

Receptors: Models for Binding, Trafficking, and Signaling

Receptors: Models for Binding, Trafficking, and Signaling PDF Author: Douglas A. Lauffenburger
Publisher: Oxford University Press, USA
ISBN: 0195106636
Category : Medical
Languages : en
Pages : 376

Book Description
This book offers a bridge at the interface between engineering and cell biology, demonstrating how a mathematical modelling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor ligand interactions. Model frameworks are described over the entire spectrum of receptor processes, from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioural functions they govern, including proliferation, adhesion, and migration.

Fractal Binding and Dissociation Kinetics for Different Biosensor Applications

Fractal Binding and Dissociation Kinetics for Different Biosensor Applications PDF Author: Ajit Sadana
Publisher: Elsevier
ISBN: 9780080458915
Category : Technology & Engineering
Languages : en
Pages : 650

Book Description
Biosensors are portable and convenient devices that permit the rapid and reliable analysis of substances. They are increasingly used in healthcare, drug design, environmental monitoring and the detection of biological, chemical, and toxic agents. Fractal Binding and Dissociation Kinetics for Different Biosensor Applications focuses on two areas of expanding biosensor development that include (a) the detection of biological and chemical pathogens in the atmosphere, and (b) biomedical applications, especially in healthcare. The author provides numerous examples of practical uses, particularly biomedical applications and the detection of biological or chemical pathogens. This book also contains valuable information dedicated to the economics of biosensors. After reading this book, the reader will gain invaluable insight into how biosensors work and how they may be used more effectively. * No other book provides a detailed kinetic analysis of the binding and dissociation reactions occurring on the biosensor surfaces * Packed with examples of practical uses of biosensors * Includes chapters dedicated to the economics of biosensors

Biophysical Approaches Determining Ligand Binding to Biomolecular Targets

Biophysical Approaches Determining Ligand Binding to Biomolecular Targets PDF Author: Alberto Podjarny
Publisher: Royal Society of Chemistry
ISBN: 1849732663
Category : Science
Languages : en
Pages : 260

Book Description
The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available.

The Binding Volume 1

The Binding Volume 1 PDF Author: John Parham
Publisher: John Parham Publishing
ISBN: 1645503399
Category : Fiction
Languages : en
Pages : 230

Book Description
What happens when a 5,000-year-old Starman, a Voodoo Queen, a sarcastic, telepathic cat, and a motley crew of former Louisiana Creole military veterans join forces to save America from a mutating Nano virus? New Orleans is Ground Zero for the Russian Mafia’s most sinister plot yet. But their plan to release a Nano virus that mutates and kills food crops is missing one vital component… water. Lucky for them, The Big Easy has plenty to spare! A band of untamed and unfettered misfits join forces to stop the Russians or watch as they destroy crops from coast-to-coast. With amazing skills, highly volatile personalities, unadulterated chaos, and more drama than a soap opera, the crew of unlikely allies must achieve the impossible. Can they do it without creating another disaster or will it be chaos? Find out in this Sci-fi Action-Adventure novel!

Odorant Binding and Chemosensory Proteins

Odorant Binding and Chemosensory Proteins PDF Author:
Publisher: Academic Press
ISBN: 012821158X
Category : Science
Languages : en
Pages : 516

Book Description
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Novel Calcium-Binding Proteins

Novel Calcium-Binding Proteins PDF Author: Claus W. Heizmann
Publisher: Springer Science & Business Media
ISBN: 364276150X
Category : Science
Languages : en
Pages : 606

Book Description
A wide variety of hormones, neurotransmitters and growth factors exert their cellular effects by reacting first with membrane receptors resulting in an increase of intracellular calcium and the cellular response. The calcium signal in the cell is mediated by the high-affinity calcium binding proteins (characterized by the EF-hand structural element), and by the calcium and phospholipid dependent proteins. Many of these have been discovered most recently. Their purification, distribution, protein and gene structures as well as their physiological roles are discussed. The book is of interest to biochemists and molecular biologists as well as to clinicians and the pharmaceutical industry who can apply the results in this field.
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