Experimental Design and Data Analysis for Biologists

Experimental Design and Data Analysis for Biologists PDF Author: Gerry P. Quinn
Publisher: Cambridge University Press
ISBN: 1139432893
Category : Nature
Languages : en
Pages : 851

Book Description
An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.

Experimental Design and Data Analysis for Biologists

Experimental Design and Data Analysis for Biologists PDF Author: Gerry P. Quinn
Publisher: Cambridge University Press
ISBN: 1107036712
Category : Mathematics
Languages : en
Pages : 409

Book Description
A biostatistics textbook for upper undergraduate and graduate students, covering analyses used by biologists and now including R code.

Experimental Design for Biologists

Experimental Design for Biologists PDF Author: David J. Glass
Publisher: CSHL Press
ISBN: 0879697350
Category : Biology
Languages : en
Pages : 211

Book Description
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Experimental Design for Laboratory Biologists

Experimental Design for Laboratory Biologists PDF Author: Stanley E. Lazic
Publisher: Cambridge University Press
ISBN: 1316810674
Category : Medical
Languages : en
Pages : 429

Book Description
Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

Statistical Methods in Biology

Statistical Methods in Biology PDF Author: S.J. Welham
Publisher: CRC Press
ISBN: 1439808783
Category : Mathematics
Languages : en
Pages : 606

Book Description
Written in simple language with relevant examples, Statistical Methods in Biology: Design and Analysis of Experiments and Regression is a practical and illustrative guide to the design of experiments and data analysis in the biological and agricultural sciences. The book presents statistical ideas in the context of biological and agricultural sciences to which they are being applied, drawing on relevant examples from the authors’ experience. Taking a practical and intuitive approach, the book only uses mathematical formulae to formalize the methods where necessary and appropriate. The text features extended discussions of examples that include real data sets arising from research. The authors analyze data in detail to illustrate the use of basic formulae for simple examples while using the GenStat® statistical package for more complex examples. Each chapter offers instructions on how to obtain the example analyses in GenStat and R. By the time you reach the end of the book (and online material) you will have gained: A clear appreciation of the importance of a statistical approach to the design of your experiments, A sound understanding of the statistical methods used to analyse data obtained from designed experiments and of the regression approaches used to construct simple models to describe the observed response as a function of explanatory variables, Sufficient knowledge of how to use one or more statistical packages to analyse data using the approaches described, and most importantly, An appreciation of how to interpret the results of these statistical analyses in the context of the biological or agricultural science within which you are working. The book concludes with a guide to practical design and data analysis. It gives you the understanding to better interact with consultant statisticians and to identify statistical approaches to add value to your scientific research.

An Introduction To Experimental Design And Statistics For Biology

An Introduction To Experimental Design And Statistics For Biology PDF Author: David Heath
Publisher: CRC Press
ISBN: 1135370117
Category : Mathematics
Languages : en
Pages : 372

Book Description
This illustrated textbook for biologists provides a refreshingly clear and authoritative introduction to the key ideas of sampling, experimental design, and statistical analysis. The author presents statistical concepts through common sense, non-mathematical explanations and diagrams. These are followed by the relevant formulae and illustrated by w

Sampling Design and Statistical Methods for Environmental Biologists

Sampling Design and Statistical Methods for Environmental Biologists PDF Author: Roger H. Green
Publisher: John Wiley & Sons
ISBN: 9780471039013
Category : Science
Languages : en
Pages : 278

Book Description
Provides--in an organized and compact source--a comprehensive guide to the principles of sampling design and statistical analysis methods. Reviews the principles of inference, sampling and statistical design, and hypothesis formulation, all with special reference to ecological data. Includes an impact study illustrating the principles presented. Contains a key to five broad categories of environmental studies--as well as examples and examines specific topics that apply to any environmental study. Provides a comprehensive bibliography which is cross-referenced to the text and keyed to a specific topic code (types of methods and environments studied).

An Introduction To Experimental Design And Statistics For Biology

An Introduction To Experimental Design And Statistics For Biology PDF Author: David Heath
Publisher: CRC Press
ISBN: 9780203499245
Category : Mathematics
Languages : en
Pages : 390

Book Description
This illustrated textbook for biologists provides a refreshingly clear and authoritative introduction to the key ideas of sampling, experimental design, and statistical analysis. The author presents statistical concepts through common sense, non-mathematical explanations and diagrams. These are followed by the relevant formulae and illustrated by w

Biostatistical Design and Analysis Using R

Biostatistical Design and Analysis Using R PDF Author: Dr Murray Logan
Publisher: John Wiley & Sons
ISBN: 144436247X
Category : Science
Languages : en
Pages : 578

Book Description
R — the statistical and graphical environment is rapidly emerging as an important set of teaching and research tools for biologists. This book draws upon the popularity and free availability of R to couple the theory and practice of biostatistics into a single treatment, so as to provide a textbook for biologists learning statistics, R, or both. An abridged description of biostatistical principles and analysis sequence keys are combined together with worked examples of the practical use of R into a complete practical guide to designing and analyzing real biological research. Topics covered include: simple hypothesis testing, graphing exploratory data analysis and graphical summaries regression (linear, multi and non-linear) simple and complex ANOVA and ANCOVA designs (including nested, factorial, blocking, spit-plot and repeated measures) frequency analysis and generalized linear models. Linear mixed effects modeling is also incorporated extensively throughout as an alternative to traditional modeling techniques. The book is accompanied by a companion website www.wiley.com/go/logan/r with an extensive set of resources comprising all R scripts and data sets used in the book, additional worked examples, the biology package, and other instructional materials and links.
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