Viral

Author: Matt Ridley
Publisher: HarperCollins
ISBN: 0063273608
Category : Medical
Languages : en
Pages : 448

Book Description
"Chan and Ridley write with an urgency...that inspires gripping depictions of what viruses are, how infectious-disease laboratories work and wonderfully lucid descriptions of bats. . . . They powerfully recount how dangerous pathogens can both leak from a lab and emerge in nature." (New York Times Book Review) Understanding how Covid-19 started is crucial for the future of humankind. Viral is the most incisive and authoritative book about the search for the source of the virus. A new virus descended on the human species in 2019 wreaking unprecedented havoc. Finding out where it came from and how it first jumped into people is an urgent priority, but early expectations that this would prove an easy question to answer have been dashed. Nearly two years into the pandemic, the crucial mystery of the origin of SARS-CoV-2 is not only unresolved but has deepened. In this uniquely insightful book, a scientist and a writer join forces to try to get to the bottom of how a virus whose closest relations live in bats in subtropical southern China somehow managed to begin spreading among people more than 1,500 kilometres away in the city of Wuhan. They grapple with the baffling fact that the virus left none of the expected traces that such outbreaks usually create: no infected market animals or wildlife, no chains of early cases in travellers to the city, no smouldering epidemic in a rural area, no rapid adaptation of the virus to its new host—human beings. To try to solve this pressing mystery, Viral delves deep into the events of 2019 leading up to 2021, the details of what went on in animal markets and virology laboratories, the records and data hidden from sight within archived Chinese theses and websites, and the clues that can be coaxed from the very text of the virus’s own genetic code. The result is a gripping detective story that takes the reader deeper and deeper into a metaphorical cave of mystery. One by one the authors explore promising tunnels only to show that they are blind alleys, until, miles beneath the surface, they find themselves tantalisingly close to a shaft that leads to the light.

Viral

Author: Helen FitzGerald
Publisher: Faber & Faber
ISBN: 0571323529
Category : Fiction
Languages : en
Pages : 220

Book Description
So far, twenty-three thousand and ninety-six people have seen me online. Su has always been the successful sister. It's Leah who is wild and often angry. But when they go to Magaluf to celebrate their exam results, Su disappears. Su is on the run, humiliated and afraid. There's an online video of her performing multiple sex acts in a nightclub. And everyone has seen it. Their mother Ruth, a prominent court judge, is furious. Can she bring justice to the men who took advantage of her daughter, and what will it take to bring Su home? 'Read it.' Stylist 'Gripping.' Tammy Cohen, author of When She Was Bad 'A real psychological roller-coaster.' Scotsman

Viral

Author: Robin Cook
Publisher: Penguin
ISBN: 0593328310
Category : Fiction
Languages : en
Pages : 513

Book Description
In this electrifying medical thriller from New York Times bestselling author Robin Cook, a family’s exposure to a rare yet deadly virus ensnares them in a growing danger to mankind—and pulls back the curtain on a healthcare system powered by profit and greed. Trying to find some normalcy during the Covid-19 pandemic, Brian Murphy and his family are on a summer excursion in Cape Cod when his wife, Emma, comes down with concerning flu-like symptoms. But their leisurely return home to New York City quickly becomes a race to the local hospital as she suddenly begins seizing in the car. At the ICU, she is diagnosed with eastern equine encephalitis, a rare and highly lethal mosquito-borne viral disease seemingly caught during one of their evening cookouts. Complicating the situation further, Brian and Emma’s young daughter then begins to exhibit alarming physical and behavioral symptoms, too. Emma’s harrowing hospital stay turns even more fraught when Brian receives a staggering hospital bill full of outrageous charges and murky language. To add insult to injury, his health insurance company refuses to cover any of the cost, citing dubious clauses in Brian’s policy. Forced to choose between the ongoing care of family and bills he can never pay, and furious at a shockingly indifferent healthcare system, Brian vows to seek justice. But to get to the bottom of the predatory practices targeting his loved ones and countless others, he must uncover the dark side of an industry that has strayed drastically from its altruistic roots—and bring down the callous executives preying on the sick and defenseless before the virus can claim even more people . . .

The Viral Underclass

Author: Steven W. Thrasher
Publisher: Celadon Books
ISBN: 1250796652
Category : Social Science
Languages : en
Pages : 240

Book Description
**LONGLISTED FOR THE 2023 PEN/JOHN KENNETH GALBRAITH AWARD FOR NONFICTION** **LONGLISTED FOR THE 2023 ANDREW CARNEGIE MEDALS FOR EXCELLENCE** **WINNER OF THE 2022 POZ AWARD FOR BEST IN LITERATURE** "An irresistibly readable and humane exploration of the barbarities of class...readers are gifted that most precious of things in these muddled times: a clear lens through which to see the world." —Naomi Klein, New York Times bestselling author of This Changes Everything and The Shock Doctrine From preeminent LGBTQ scholar, social critic, and journalist Steven W. Thrasher comes a powerful and crucial exploration of one of the most pressing issues of our times: how viruses expose the fault lines of society. Having spent a ground-breaking career studying the racialization, policing, and criminalization of HIV, Dr. Thrasher has come to understand a deeper truth at the heart of our society: that there are vast inequalities in who is able to survive viruses and that the ways in which viruses spread, kill, and take their toll are much more dependent on social structures than they are on biology alone. Told through the heart-rending stories of friends, activists, and teachers navigating the novel coronavirus, HIV, and other viruses, Dr. Thrasher brings the reader with him as he delves into the viral underclass and lays bare its inner workings. In the tradition of Isabel Wilkerson’s Caste and Michelle Alexander’s The New Jim Crow, The Viral Underclass helps us understand the world more deeply by showing the fraught relationship between privilege and survival.

Understanding Viruses

Author: Teri Shors
Publisher: Jones & Bartlett Publishers
ISBN: 1449677541
Category : Science
Languages : en
Pages : 732

Book Description
The ideal text for undergraduate students majoring in biology, microbiology, medical technology, or pre-med, the Second Edition of Understanding Viruses provides a balanced approach to this fascinating discipline, combining the molecular, clinical, and historical aspects of virology. Updated throughout to keep pace with this fast-paced field, the text provides a strong, comprehensive introduction to human viral diseases. New material on molecular virology as well as new virus families presented coupled with chapters on viral diseases of animals; the history of clinical trials, gene therapy, and xenotranplantation; prions and viroids; plant viruses; and bacteriophages add to the scope of the text. Chapters discussing specific viral diseases weave in an epidemiological and global perspective and include treatment and prevention information. Contemporary case studies, Refresher Boxes, and Virus Files engage students in the learning process. With a wealth of student and instructor support tools, Understanding Viruses is an accessible, exciting, and engaging text for your virology course.

Viruses

Author: Susan Payne
Publisher: Academic Press
ISBN: 0128031107
Category : Science
Languages : en
Pages : 354

Book Description
Viruses: From Understanding to Investigation provides students with a map for lifetime learning by presenting the definition and unique characteristics of viruses, including major topics, such as the virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study viruses. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work. - Employs a comparative strategy to emphasize unique structural and molecular characteristics that inform transmission, disease processes, vaccine strategies and host responses - Presents a review of host cell and molecular biology and the immune system - Features topical areas of research, including genomics in virus discovery, the virome, and beneficial interactions between viruses and their hosts - Includes text boxes throughout with experimental approaches used by virologists - Covers learning objectives for each chapter, methods and advances, question sets, quizzes and a glossary

Genomics and computational science for virus research

Author: Hironori Sato
Publisher: Frontiers E-books
ISBN: 2889191265
Category :
Languages : en
Pages : 183

Book Description
A biologically striking and clinically important feature of viruses is their rapid evolutionary dynamics in nature. The continual interactions between viruses and host organisms promote quick changes in virus populations, eventually leading to co-evolution of viruses and hosts for their survival. The structural and functional information on the interactions between viruses and hosts should provide a molecular and biological basis to understand infection, replication, cell/host-tropism, immune escape, pathogenesis, and direction of evolution of viruses. The information is also essential to develop methods to control transmission and replication of pathogenic viruses. However, the integrated information on the structure, function, and evolution of viruses and hosts has remained poorly accumulated, partly due to the limitation of analytical methods. Recent progress in genome science and computational approach may open up a new avenue of research of the interactions between viruses and hosts by integrating information on the structures, functions, and evolution. In this Research Topic, we welcome papers concerning the computer-assisted structural and functional studies based on genomic information, with theoretical or in combination with experimental approaches, for understanding molecules, infection, replication, cell/host-tropism, immune escape, pathogenesis, and evolution of viruses in nature.

Unconventional Agents and Unclassified Viruses

Author: O.-R. Kaaden
Publisher: Springer Science & Business Media
ISBN: 3709193001
Category : Science
Languages : en
Pages : 307

Book Description
Among unconventional agents and unclassified viruses the contributions to this volume focused on prion-related diseases, with special emphasis on bovine spongiform encephalopathy and human spongiform encephalopathies, and Borna disease virus, an agent known since long time to be pathogenic for horses and sheep, which is now discussed as a potential pathogen for humans. Additionally, the volume contains articles about newly discovered viruses like porcine respiratory and reproductive syndrome virus and viruses that are classified only provisionally like African swine fever virus, hepatitis C and E viruses, or the arteriviruses.

Highly Mutable Animal RNA Viruses: Adaptation and Evolution

Author: Akio Adachi
Publisher: Frontiers Media SA
ISBN: 2889453480
Category :
Languages : en
Pages : 421

Book Description
Viruses are widely present in nature, and numerous viral species with a variety of unique characteristics have been identified so far. Even now, new emerging or re-emerging viruses are being found or re-found as novel viral classes or as quasi-species. Indeed, viruses are everywhere. Of note, viruses are pivotal as targets and tools of basic and applied sciences. On one hand, portions of the viruses are infectious for animals including humans, and cause various diseases in infected hosts by distinct mechanisms and at a different level of severity. While many of viruses are known to co-exist quietly with their hosts, pathogenic viruses certainly affect and threaten our society as well as individuals to provoke serious medical or economic attention. We should act against certain dreadful and highly infectious viruses as a global problem. Animal RNA viruses can readily mutate to adapt themselves in their hostile environments for their survival. Resultant viruses may sometimes show essentially altered phenotypes from the original parental strains. This fundamental and general property of animal RNA viruses represents major extensive issues of scientific, medical, and/or economic importance. In this Research Topic, we have focused on the high mutability of animal RNA viruses, and selected relevant articles on animal viruses of broad-ranges such as primate lentiviruses, influenza viruses, paramyxoviruses, flaviviruses, rabies virus, norovirus, picornaviruses, and picobirnavirus. Each article has taken up intriguing aspects of the subject viruses. We are sure that readers acquire important information on virus mutation, adaptation, diversification, and evolution, and hope that researchers in the field related to virology gain some solid hints from the reported articles for further virological and /or medical studies. Finally, we thank all the contributing researchers in this Research Topic, entitled “Highly Mutable Animal RNA Viruses: Adaptation and Evolution”, for their elegant and interesting works.

Molecular and Cellular Biology of Viruses

Author: Phoebe Lostroh
Publisher: CRC Press
ISBN: 1040005330
Category : Science
Languages : en
Pages : 550

Book Description
This fully revised second edition of Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered, with separate chapters for their replication and expression strategies, and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given at the back of the book. Examples come from the most-studied and medically important viruses such as SARS-CoV-2, HIV, and influenza. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses, with a separate chapter on medical applications such as antiviral drugs and vaccine development. The final chapter is on virus diversity and evolution, incorporating contemporary insights from metagenomic research. The second edition has updated suggestions for primary literature to discuss along with each chapter. New to this second edition, a supplementary chapter, freely available for download, looks at how virology intersects with public health, and uses the COVID-19 pandemic as a notable example. Key Features Readable but rigorous coverage of the molecular and cellular biology of viruses Molecular mechanisms of all major groups, including plant viruses and bacteriophages, illustrated by example Host-pathogen interactions at the cellular and molecular level emphasized throughout Medical implications and consequences included Quality illustrations available to instructors New to this second edition, interactive quiz questions hosted online