Author: Nick Lane
Publisher: OUP Oxford
ISBN: 9780191513015
Category : Science
Languages : en
Pages : 370
Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
Life Ascending
Author: Nick Lane
Publisher: Profile Books
ISBN: 1847652220
Category : Science
Languages : en
Pages : 353
Book Description
Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.
Publisher: Profile Books
ISBN: 1847652220
Category : Science
Languages : en
Pages : 353
Book Description
Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.
Oxygen
Author: Nick Lane
Publisher: Oxford University Press, USA
ISBN: 0198607830
Category : Health & Fitness
Languages : en
Pages : 385
Book Description
Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. Damage to DNA caused by oxidative stress appears to explain aging and many of its diseases, hence the popularity in alternative health circles of antioxidants. But antioxidants alone fail to prevent aging. Lane suggests two different avenues of study: modulation of the immune system, which generates free radicals as part of its defense against infectious diseases; and ways of improving the health of our cellular mitochondria, on which many age-related ailments seem to depend. Provocative and complexly argued. Copyright ©Kirkus Reviews, used with permission.
Publisher: Oxford University Press, USA
ISBN: 0198607830
Category : Health & Fitness
Languages : en
Pages : 385
Book Description
Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. Damage to DNA caused by oxidative stress appears to explain aging and many of its diseases, hence the popularity in alternative health circles of antioxidants. But antioxidants alone fail to prevent aging. Lane suggests two different avenues of study: modulation of the immune system, which generates free radicals as part of its defense against infectious diseases; and ways of improving the health of our cellular mitochondria, on which many age-related ailments seem to depend. Provocative and complexly argued. Copyright ©Kirkus Reviews, used with permission.
Suicide of a Superpower
Author: Patrick J. Buchanan
Publisher: Macmillan
ISBN: 1429990600
Category : Political Science
Languages : en
Pages : 497
Book Description
The New York Times–bestselling conservative author explains why he believes certain social trends will lead to the downfall of the United States. America is disintegrating. The “one Nation under God, indivisible” of the Pledge of Allegiance is passing away. In a few decades, that America will be gone forever. In its place will arise a country unrecognizable to our parents. This is the thrust of Pat Buchanan’s Suicide of a Superpower, his most controversial and thought-provoking book to date. Buchanan traces the disintegration to three historic changes: America’s loss of her cradle faith, Christianity; the moral, social, and cultural collapse that have followed from that loss; and the slow death of the people who created and ruled the nation. And as our nation disintegrates, our government is failing in its fundamental duties, unable to defend our borders, balance our budgets, or win our wars. How Americans are killing the country they profess to love, and the fate that awaits us if we do not turn around, is what Suicide of a Superpower is all about. Praise for Suicide of a Superpower “Suicide of a Superpower traces the changes in governance and culture in America that foreshadow a decline of epic proportions. . . . Buchanan is no stranger to controversy. Nor is he prone to exaggerate. The crises he describes are real, and he is not afraid to say they ‘may prove too much for our democracy to cope with.’” —Jack Kenny, The New American Magazine “Progressives may recoil at these assertions as well as his positions on immigration, affirmative action and morality, though they may share his sentiments regarding war and America’s unnecessary military presence around the world. Not to disappoint his loyal followers, Buchanan reveals the essence of conservative thought and its origins with clarity and precision.” —Publishers Weekly
Publisher: Macmillan
ISBN: 1429990600
Category : Political Science
Languages : en
Pages : 497
Book Description
The New York Times–bestselling conservative author explains why he believes certain social trends will lead to the downfall of the United States. America is disintegrating. The “one Nation under God, indivisible” of the Pledge of Allegiance is passing away. In a few decades, that America will be gone forever. In its place will arise a country unrecognizable to our parents. This is the thrust of Pat Buchanan’s Suicide of a Superpower, his most controversial and thought-provoking book to date. Buchanan traces the disintegration to three historic changes: America’s loss of her cradle faith, Christianity; the moral, social, and cultural collapse that have followed from that loss; and the slow death of the people who created and ruled the nation. And as our nation disintegrates, our government is failing in its fundamental duties, unable to defend our borders, balance our budgets, or win our wars. How Americans are killing the country they profess to love, and the fate that awaits us if we do not turn around, is what Suicide of a Superpower is all about. Praise for Suicide of a Superpower “Suicide of a Superpower traces the changes in governance and culture in America that foreshadow a decline of epic proportions. . . . Buchanan is no stranger to controversy. Nor is he prone to exaggerate. The crises he describes are real, and he is not afraid to say they ‘may prove too much for our democracy to cope with.’” —Jack Kenny, The New American Magazine “Progressives may recoil at these assertions as well as his positions on immigration, affirmative action and morality, though they may share his sentiments regarding war and America’s unnecessary military presence around the world. Not to disappoint his loyal followers, Buchanan reveals the essence of conservative thought and its origins with clarity and precision.” —Publishers Weekly
Love, Sex, Fear, Death
Author: Timothy Wyllie
Publisher: Feral House
ISBN: 1932595376
Category : Religion
Languages : en
Pages : 306
Book Description
The Process Church is one of the most controversial cults of modern times. Its apocalyptic ideas and powerful literature brought on extreme allegiances and shocking accusations. Here, the secretive group's history is finally revealed for the first time. Through its various incarnations, the Process Church has kept its history sealed for decades. Though the church was not as horrifying as some made it out to be, its actual history is truly unexpected and sensational.
Publisher: Feral House
ISBN: 1932595376
Category : Religion
Languages : en
Pages : 306
Book Description
The Process Church is one of the most controversial cults of modern times. Its apocalyptic ideas and powerful literature brought on extreme allegiances and shocking accusations. Here, the secretive group's history is finally revealed for the first time. Through its various incarnations, the Process Church has kept its history sealed for decades. Though the church was not as horrifying as some made it out to be, its actual history is truly unexpected and sensational.
Breakdown
Author: Eileen McNamara
Publisher:
ISBN: 9780671796211
Category : Law
Languages : en
Pages : 380
Book Description
This is the critically-acclaimed true account of the promising young Harvard student's suicide and the bizarre and controversial therapy of his psychiatrist as written by Boston Globe reporter Eileen McNamara. This is a story that has made national headlines.
Publisher:
ISBN: 9780671796211
Category : Law
Languages : en
Pages : 380
Book Description
This is the critically-acclaimed true account of the promising young Harvard student's suicide and the bizarre and controversial therapy of his psychiatrist as written by Boston Globe reporter Eileen McNamara. This is a story that has made national headlines.
Power, Money and Sex
Author: Deion Sanders
Publisher:
ISBN: 9780849937767
Category : Biography & Autobiography
Languages : en
Pages : 260
Book Description
Superstar Deion Sanders tells his powerful life story and reveals how power, money and sex could not satisfy the void in his life-a void ultimately satisfied by his relationship with Christ. A photo section included in this national best-seller.
Publisher:
ISBN: 9780849937767
Category : Biography & Autobiography
Languages : en
Pages : 260
Book Description
Superstar Deion Sanders tells his powerful life story and reveals how power, money and sex could not satisfy the void in his life-a void ultimately satisfied by his relationship with Christ. A photo section included in this national best-seller.
The Neurobiological Basis of Suicide
Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485
Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485
Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Hello Cruel World
Author: Kate Bornstein
Publisher: Seven Stories Press
ISBN: 1583229663
Category : Social Science
Languages : en
Pages : 242
Book Description
Celebrated transsexual trailblazer Kate Bornstein has, with more humor and spunk than any other, ushered us into a world of limitless possibility through a daring re-envisionment of the gender system as we know it. Here, Bornstein bravely and wittily shares personal and unorthodox methods of survival in an often cruel world. A one-of-a-kind guide to staying alive outside the box, Hello, Cruel World is a much-needed unconventional approach to life for those who want to stay on the edge, but alive. Hello, Cruel World features a catalog of 101 alternatives to suicide that range from the playful (moisturize!), to the irreverent (shatter some family values), to the highly controversial. Designed to encourage readers to give themselves permission to unleash their hearts' harmless desires, the book has only one directive: "Don't be mean." It is this guiding principle that brings its reader on a self-validating journey, which forges wholly new paths toward a resounding decision to choose life. Tenderly intimate and unapologetically edgy, Kate Bornstein is the radical role model, the affectionate best friend, and the guiding mentor all in one.
Publisher: Seven Stories Press
ISBN: 1583229663
Category : Social Science
Languages : en
Pages : 242
Book Description
Celebrated transsexual trailblazer Kate Bornstein has, with more humor and spunk than any other, ushered us into a world of limitless possibility through a daring re-envisionment of the gender system as we know it. Here, Bornstein bravely and wittily shares personal and unorthodox methods of survival in an often cruel world. A one-of-a-kind guide to staying alive outside the box, Hello, Cruel World is a much-needed unconventional approach to life for those who want to stay on the edge, but alive. Hello, Cruel World features a catalog of 101 alternatives to suicide that range from the playful (moisturize!), to the irreverent (shatter some family values), to the highly controversial. Designed to encourage readers to give themselves permission to unleash their hearts' harmless desires, the book has only one directive: "Don't be mean." It is this guiding principle that brings its reader on a self-validating journey, which forges wholly new paths toward a resounding decision to choose life. Tenderly intimate and unapologetically edgy, Kate Bornstein is the radical role model, the affectionate best friend, and the guiding mentor all in one.