Practical Computing for Biologists

Author: Steven H.D. Haddock
Publisher: Sinauer
ISBN: 9780878933914
Category : Medical
Languages : en
Pages : 0

Book Description
Practical Computing for Biologists shows you how to use many freely available computing tools to work more powerfully and effectively. The book was born out of the authors' own experience in developing tools for their research and helping other biologists with their computational problems. Many of the techniques are relevant to molecular bioinformatics but the scope of the book is much broader, covering topics and techniques that are applicable to a range of scientific endeavours. Twenty-two chapters organized into six parts address the following topics (and more; see Contents): • Searching with regular expressions • The Unix command line • Python programming and debugging • Creating and editing graphics • Databases • Performing analyses on remote servers • Working with electronics While the main narrative focuses on Mac OS X, most of the concepts and examples apply to any operating system. Where there are differences for Windows and Linux users, parallel instructions are provided in the margin and in an appendix. The book is designed to be used as a self-guided resource for researchers, a companion book in a course, or as a primary textbook. Practical Computing for Biologists will free you from the most frustrating and time-consuming aspects of data processing so you can focus on the pleasures of scientific inquiry.

Computing for Biologists

Author: Ran Libeskind-Hadas
Publisher: Cambridge University Press
ISBN: 1316061337
Category : Science
Languages : en
Pages : 289

Book Description
Computing is revolutionizing the practice of biology. This book, which assumes no prior computing experience, provides students with the tools to write their own Python programs and to understand fundamental concepts in computational biology and bioinformatics. Each major part of the book begins with a compelling biological question, followed by the algorithmic ideas and programming tools necessary to explore it: the origins of pathogenicity are examined using gene finding, the evolutionary history of sex determination systems is studied using sequence alignment, and the origin of modern humans is addressed using phylogenetic methods. In addition to providing general programming skills, this book explores the design of efficient algorithms, simulation, NP-hardness, and the maximum likelihood method, among other key concepts and methods. Easy-to-read and designed to equip students with the skills to write programs for solving a range of biological problems, the book is accompanied by numerous programming exercises, available at www.cs.hmc.edu/CFB.

Computing Skills for Biologists

Author: Stefano Allesina
Publisher: Princeton University Press
ISBN: 0691182752
Category : Computers
Languages : en
Pages : 440

Book Description
A concise introduction to key computing skills for biologists While biological data continues to grow exponentially in size and quality, many of today’s biologists are not trained adequately in the computing skills necessary for leveraging this information deluge. In Computing Skills for Biologists, Stefano Allesina and Madlen Wilmes present a valuable toolbox for the effective analysis of biological data. Based on the authors’ experiences teaching scientific computing at the University of Chicago, this textbook emphasizes the automation of repetitive tasks and the construction of pipelines for data organization, analysis, visualization, and publication. Stressing practice rather than theory, the book’s examples and exercises are drawn from actual biological data and solve cogent problems spanning the entire breadth of biological disciplines, including ecology, genetics, microbiology, and molecular biology. Beginners will benefit from the many examples explained step-by-step, while more seasoned researchers will learn how to combine tools to make biological data analysis robust and reproducible. The book uses free software and code that can be run on any platform. Computing Skills for Biologists is ideal for scientists wanting to improve their technical skills and instructors looking to teach the main computing tools essential for biology research in the twenty-first century. Excellent resource for acquiring comprehensive computing skills Both novice and experienced scientists will increase efficiency by building automated and reproducible pipelines for biological data analysis Code examples based on published data spanning the breadth of biological disciplines Detailed solutions provided for exercises in each chapter Extensive companion website

Python Programming for Biology

Author: Tim J. Stevens
Publisher: Cambridge University Press
ISBN: 1316194140
Category : Science
Languages : en
Pages : 721

Book Description
Do you have a biological question that could be readily answered by computational techniques, but little experience in programming? Do you want to learn more about the core techniques used in computational biology and bioinformatics? Written in an accessible style, this guide provides a foundation for both newcomers to computer programming and those interested in learning more about computational biology. The chapters guide the reader through: a complete beginners' course to programming in Python, with an introduction to computing jargon; descriptions of core bioinformatics methods with working Python examples; scientific computing techniques, including image analysis, statistics and machine learning. This book also functions as a language reference written in straightforward English, covering the most common Python language elements and a glossary of computing and biological terms. This title will teach undergraduates, postgraduates and professionals working in the life sciences how to program with Python, a powerful, flexible and easy-to-use language.

Bioinformatics Computing

Author: Bryan P. Bergeron
Publisher: Prentice Hall Professional
ISBN: 9780131008250
Category : Computers
Languages : en
Pages : 472

Book Description
Comprehensive and concise, this handbook has chapters on computing visualization, large database designs, advanced pattern matching and other key bioinformatics techniques. It is a practical guide to computing in the growing field of Bioinformatics--the study of how information is represented and transmitted in biological systems, starting at the molecular level.

Bioinformatics Data Skills

Author: Vince Buffalo
Publisher: "O'Reilly Media, Inc."
ISBN: 1449367518
Category : Computers
Languages : en
Pages : 538

Book Description
Learn the data skills necessary for turning large sequencing datasets into reproducible and robust biological findings. With this practical guide, youâ??ll learn how to use freely available open source tools to extract meaning from large complex biological data sets. At no other point in human history has our ability to understand lifeâ??s complexities been so dependent on our skills to work with and analyze data. This intermediate-level book teaches the general computational and data skills you need to analyze biological data. If you have experience with a scripting language like Python, youâ??re ready to get started. Go from handling small problems with messy scripts to tackling large problems with clever methods and tools Process bioinformatics data with powerful Unix pipelines and data tools Learn how to use exploratory data analysis techniques in the R language Use efficient methods to work with genomic range data and range operations Work with common genomics data file formats like FASTA, FASTQ, SAM, and BAM Manage your bioinformatics project with the Git version control system Tackle tedious data processing tasks with with Bash scripts and Makefiles

Developing Bioinformatics Computer Skills

Author: Cynthia Gibas
Publisher: "O'Reilly Media, Inc."
ISBN: 9781565926646
Category : Computers
Languages : en
Pages : 452

Book Description
This practical, hands-on guide shows how to develop a structured approach to biological data and the tools needed to analyze it. It's aimed at scientists and students learning computational approaches to biological data, as well as experienced biology researchers starting to use computers to handle data.

Practical Statistics for Field Biology

Author: Jim Fowler
Publisher: John Wiley & Sons
ISBN: 1118685644
Category : Science
Languages : en
Pages : 235

Book Description
Provides an excellent introductory text for students on the principles and methods of statistical analysis in the life sciences, helping them choose and analyse statistical tests for their own problems and present their findings. An understanding of statistical principles and methods is essential for any scientist but is particularly important for those in the life sciences. The field biologist faces very particular problems and challenges with statistics as "real-life" situations such as collecting insects with a sweep net or counting seagulls on a cliff face can hardly be expected to be as reliable or controllable as a laboratory-based experiment. Acknowledging the peculiarites of field-based data and its interpretation, this book provides a superb introduction to statistical analysis helping students relate to their particular and often diverse data with confidence and ease. To enhance the usefulness of this book, the new edition incorporates the more advanced method of multivariate analysis, introducing the nature of multivariate problems and describing the the techniques of principal components analysis, cluster analysis and discriminant analysis which are all applied to biological examples. An appendix detailing the statistical computing packages available has also been included. It will be extremely useful to undergraduates studying ecology, biology, and earth and environmental sciences and of interest to postgraduates who are not familiar with the application of multiavirate techniques and practising field biologists working in these areas.

Beginning Perl for Bioinformatics

Author: James Tisdall
Publisher: "O'Reilly Media, Inc."
ISBN: 0596550472
Category : Computers
Languages : en
Pages : 388

Book Description
With its highly developed capacity to detect patterns in data, Perl has become one of the most popular languages for biological data analysis. But if you're a biologist with little or no programming experience, starting out in Perl can be a challenge. Many biologists have a difficult time learning how to apply the language to bioinformatics. The most popular Perl programming books are often too theoretical and too focused on computer science for a non-programming biologist who needs to solve very specific problems.Beginning Perl for Bioinformatics is designed to get you quickly over the Perl language barrier by approaching programming as an important new laboratory skill, revealing Perl programs and techniques that are immediately useful in the lab. Each chapter focuses on solving a particular bioinformatics problem or class of problems, starting with the simplest and increasing in complexity as the book progresses. Each chapter includes programming exercises and teaches bioinformatics by showing and modifying programs that deal with various kinds of practical biological problems. By the end of the book you'll have a solid understanding of Perl basics, a collection of programs for such tasks as parsing BLAST and GenBank, and the skills to take on more advanced bioinformatics programming. Some of the later chapters focus in greater detail on specific bioinformatics topics. This book is suitable for use as a classroom textbook, for self-study, and as a reference.The book covers: Programming basics and working with DNA sequences and strings Debugging your code Simulating gene mutations using random number generators Regular expressions and finding motifs in data Arrays, hashes, and relational databases Regular expressions and restriction maps Using Perl to parse PDB records, annotations in GenBank, and BLAST output

Computational Biology

Author: Röbbe Wünschiers
Publisher: Springer Science & Business Media
ISBN: 3642185525
Category : Science
Languages : en
Pages : 291

Book Description
-Teaches the reader how to use Unix, which is the key to basic computing and allows the most flexibility for bioinformatics applications -Written specifically with the needs of molecular biologists in mind -Easy to follow, written for beginners with no computational knowledge -Includes examples from biological data analysis -Can be use either for self-teaching or in courses