The Revolutionary Phenotype: The amazing story of how life begins and how it ends

The Revolutionary Phenotype: The amazing story of how life begins and how it ends PDF Author: J. -F. Gariépy
Publisher: Lulu.com
ISBN: 0359570798
Category : Science
Languages : en
Pages : 142

Book Description
The Revolutionary Phenotype is a science book that brings us four billion years into the past, when the first living molecules showed up on Planet Earth. Unlike what was previously thought, we learn that DNA-based life did not emerge from random events in a primordial soup. Indeed, the first molecules of DNA were fabricated by a previous life form. By describing the fascinating events referred to as Phenotypic Revolutions, this book provides a dire warning to humanity: if humans continue to play with their own genes, we will be the next life form to fall to our own creation.

The Selfish Gene

The Selfish Gene PDF Author: Richard Dawkins
Publisher: Oxford University Press, USA
ISBN: 9780192860927
Category : Medical
Languages : en
Pages : 372

Book Description
Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

Developmental Plasticity and Evolution

Developmental Plasticity and Evolution PDF Author: Mary Jane West-Eberhard
Publisher: Oxford University Press
ISBN: 0198028563
Category : Science
Languages : en
Pages : 815

Book Description
The first comprehensive synthesis on development and evolution: it applies to all aspects of development, at all levels of organization and in all organisms, taking advantage of modern findings on behavior, genetics, endocrinology, molecular biology, evolutionary theory and phylogenetics to show the connections between developmental mechanisms and evolutionary change. This book solves key problems that have impeded a definitive synthesis in the past. It uses new concepts and specific examples to show how to relate environmentally sensitive development to the genetic theory of adaptive evolution and to explain major patterns of change. In this book development includes not only embryology and the ontogeny of morphology, sometimes portrayed inadequately as governed by "regulatory genes," but also behavioral development and physiological adaptation, where plasticity is mediated by genetically complex mechanisms like hormones and learning. The book shows how the universal qualities of phenotypes--modular organization and plasticity--facilitate both integration and change. Here you will learn why it is wrong to describe organisms as genetically programmed; why environmental induction is likely to be more important in evolution than random mutation; and why it is crucial to consider both selection and developmental mechanism in explanations of adaptive evolution. This book satisfies the need for a truly general book on development, plasticity and evolution that applies to living organisms in all of their life stages and environments. Using an immense compendium of examples on many kinds of organisms, from viruses and bacteria to higher plants and animals, it shows how the phenotype is reorganized during evolution to produce novelties, and how alternative phenotypes occupy a pivotal role as a phase of evolution that fosters diversification and speeds change. The arguments of this book call for a new view of the major themes of evolutionary biology, as shown in chapters on gradualism, homology, environmental induction, speciation, radiation, macroevolution, punctuation, and the maintenance of sex. No other treatment of development and evolution since Darwin's offers such a comprehensive and critical discussion of the relevant issues. Developmental Plasticity and Evolution is designed for biologists interested in the development and evolution of behavior, life-history patterns, ecology, physiology, morphology and speciation. It will also appeal to evolutionary paleontologists, anthropologists, psychologists, and teachers of general biology.

Rethinking Evolution: The Revolution That's Hiding In Plain Sight

Rethinking Evolution: The Revolution That's Hiding In Plain Sight PDF Author: Gene Levinson
Publisher: World Scientific
ISBN: 1786347288
Category : Science
Languages : en
Pages : 498

Book Description
Rethinking Evolution links Darwin's early insights to the molecular realm inside living cells. This updated evolutionary synthesis provides an accessible explanation for biological complexity that cuts through the confusion surrounding evolutionary theory in a practical way.In addition to a wide-ranging survey of proposed updates to the modern synthesis, this title provides extraordinary new insights including emergent evolutionary potential and the generative phenotype. Drawing on well-characterized empirical facts, Rethinking Evolution transcends classical Darwinian natural selection while retaining those core principles that have stood the test of time.The updated synthesis brings a broad spectrum of specialized research together to provide a more plausible naturalistic explanation for biological evolution than ever before. Perspectives ranging from the role of energy in the origin of life to the networks of protein-DNA interactions that govern multicellular development are woven together in a robust conceptual fabric consistent with 21st century cutting-edge research.Inspired in part by the surprising ways that DNA sequences change — such as his early discovery of a fundamental mispairing mechanism by which DNA sequences expand — and drawing on a career's worth of experience both as a research scientist as well as a biology and chemistry tutor — the author provides an engaging account that is essential reading — both for the public awareness and understanding of the science of evolution and for students and professionals in the biomedical sciences.Related Link(s)

The Flexible Phenotype

The Flexible Phenotype PDF Author: Theunis Piersma
Publisher: Oxford University Press
ISBN: 0199233721
Category : Medical
Languages : en
Pages : 249

Book Description
In essence, the authors argue for the existence of direct, measurable, links between phenotype and ecology.

The Creative Destruction of Medicine

The Creative Destruction of Medicine PDF Author: Eric Topol
Publisher:
ISBN: 0465025501
Category : Health & Fitness
Languages : en
Pages : 322

Book Description
A professor of medicine reveals how technology like wireless internet, individual data, and personal genomics can be used to save lives.

The Epigenetics Revolution

The Epigenetics Revolution PDF Author: Nessa Carey
Publisher: Columbia University Press
ISBN: 0231530714
Category : Science
Languages : en
Pages : 353

Book Description
Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

The Revolutionary Origins of Life and Death

The Revolutionary Origins of Life and Death PDF Author: Pierre M. Durand
Publisher: University of Chicago Press
ISBN: 022674793X
Category : Science
Languages : en
Pages : 236

Book Description
The question of why an individual would actively kill itself has long been an evolutionary mystery. Pierre M. Durand’s ambitious book answers this question through close inspection of life and death in the earliest cellular life. As Durand shows us, cell death is a fascinating lens through which to examine the interconnectedness, in evolutionary terms, of life and death. It is a truism to note that one does not exist without the other, but just how does this play out in evolutionary history? These two processes have been studied from philosophical, theoretical, experimental, and genomic angles, but no one has yet integrated the information from these various disciplines. In this work, Durand synthesizes cellular studies of life and death looking at the origin of life and the evolutionary significance of programmed cellular death. The exciting and unexpected outcome of Durand’s analysis is the realization that life and death exhibit features of coevolution. The evolution of more complex cellular life depended on the coadaptation between traits that promote life and those that promote death. In an ironic twist, it becomes clear that, in many circumstances, programmed cell death is essential for sustaining life.

Molecular Photofitting

Molecular Photofitting PDF Author: Tony Frudakis Ph.D.
Publisher: Elsevier
ISBN: 0080551378
Category : Law
Languages : en
Pages : 711

Book Description
In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects. Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system. - Explains how physical descriptions of individuals can be generated using only their DNA - Contains case studies that show how this new forensic technology is used in practical application - Includes over 100 diagrams, tables, and photos to illustrate and outline complex concepts

Reproductomics

Reproductomics PDF Author: José A. Horcajadas
Publisher: Academic Press
ISBN: 0128126760
Category : Medical
Languages : en
Pages : 428

Book Description
Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. - Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine - Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data - Features chapter contributions by leading international experts
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