Experimental Design for the Life Sciences

Experimental Design for the Life Sciences PDF Author: Graeme Ruxton
Publisher: Oxford University Press, USA
ISBN: 0199569126
Category : Education
Languages : en
Pages : 197

Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.

Experimental Design for the Life Sciences

Experimental Design for the Life Sciences PDF Author: Graeme D. Ruxton
Publisher:
ISBN: 9780191975202
Category : Experimental design
Languages : en
Pages : 0

Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.

Principles of Experimental Design for the Life Sciences

Principles of Experimental Design for the Life Sciences PDF Author: Murray R. Selwyn
Publisher: CRC Press
ISBN: 9780849394614
Category : Science
Languages : en
Pages : 176

Book Description
Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!

Experimental Design and Data Analysis for Biologists

Experimental Design and Data Analysis for Biologists PDF Author: Gerry P. Quinn
Publisher: Cambridge University Press
ISBN: 1139432893
Category : Nature
Languages : en
Pages : 851

Book Description
An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.

Experimental Design for Biologists

Experimental Design for Biologists PDF Author: David J. Glass
Publisher: CSHL Press
ISBN: 0879697350
Category : Biology
Languages : en
Pages : 211

Book Description
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Experimental Design for Laboratory Biologists

Experimental Design for Laboratory Biologists PDF Author: Stanley E. Lazic
Publisher: Cambridge University Press
ISBN: 1316810674
Category : Medical
Languages : en
Pages : 429

Book Description
Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

Experimental Design for the Life Sciences

Experimental Design for the Life Sciences PDF Author: Graeme D. Ruxton
Publisher: Oxford University Press, USA
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 188

Book Description
Experimental Design for the Life Sciences teaches the reader how to effectively design experiments, to ensure that today's students are equipped with the skills they need to be the researchers of tomorrow. With a refreshingly approachable and articulate style, the book explains the essential elements of experimental design in clear, practical terms, so that the reader can grasp and apply even the most challenging concepts, including power analysis and pseudoreplication.

Design of Experiments for Agriculture and the Natural Sciences

Design of Experiments for Agriculture and the Natural Sciences PDF Author: Reza Hoshmand
Publisher: CRC Press
ISBN: 1420010646
Category : Mathematics
Languages : en
Pages : 456

Book Description
Written to meet the needs of both students and applied researchers, Design of Experiments for Agriculture and the Natural Sciences, Second Edition serves as an introductory guide to experimental design and analysis. Like the popular original, this thorough text provides an understanding of the logical underpinnings of design and analysis by selecting and discussing only those carefully chosen designs that offer the greatest utility. However, it improves on the first edition by adhering to a step-by-step process that greatly improves accessibility and understanding. Real problems from different areas of agriculture and science are presented throughout to show how practical issues of design and analysis are best handled. Completely revised to greatly enhance readability, this new edition includes: A new chapter on covariance analysis to help readers reduce errors, while enhancing their ability to examine covariances among selected variables Expanded material on multiple regression and variance analysis Additional examples, problems, and case studies A step-by-step Minitab® guide to help with data analysis Intended for those in the agriculture, environmental, and natural science fields as well as statisticians, this text requires no previous exposure to analysis of variance, although some familiarity with basic statistical fundamentals is assumed. In keeping with the book's practical orientation, numerous workable problems are presented throughout to reinforce the reader's ability to creatively apply the principles and concepts in any given situation.

The Design of Experiments in Neuroscience

The Design of Experiments in Neuroscience PDF Author: Mary E. Harrington
Publisher: Cambridge University Press
ISBN: 1108656331
Category : Psychology
Languages : en
Pages : 201

Book Description
Using engaging prose, Mary E. Harrington introduces neuroscience students to the principles of scientific research including selecting a topic, designing an experiment, analyzing data, and presenting research. This new third edition updates and clarifies the book's wealth of examples while maintaining the clear and effective practical advice of the previous editions. New and expanded topics in this edition include techniques such as optogenetics and conditional transgenes as well as a discussion of rigor and reproducibility in neuroscience research. Extended coverage of descriptive and inferential statistics arms readers with the analytical tools needed to interpret data. Throughout, practical guidelines are provided on avoiding experimental design problems, presenting research including creating posters and giving talks, and using a '12-step guide' to reading scientific journal articles.

Concise Handbook of Experimental Methods for the Behavioral and Biological Sciences

Concise Handbook of Experimental Methods for the Behavioral and Biological Sciences PDF Author: Jay E. Gould
Publisher: CRC Press
ISBN: 1420040863
Category : Mathematics
Languages : en
Pages : 447

Book Description
Although there are many books written on the principles and methods of experimentation, few are written in a succinct, comprehensive outline format. The Concise Handbook of Experimental Methods for the Behavioral and Biological Sciences is based on a popular course taught by the author for more than two decades to assist advanced undergraduate and
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