Author: Janny Wurts Publisher: ISBN: Category : Arithon s'Ffalenn (Fictitious character) Languages : en Pages : 0
Book Description
Betrayed and double-crossed, Arithon s'Ffalenn is held captive by the Order of the Koriathain. The desperate Fellowship Sorcerers have gambled the weal of Athera and forced through the perilous bargain that spared him, as the last Prince of Rathain, and their sole hope of unity. To suspend the Prime Matriarch's decree of execution, Arithon lives only to battle Marak's horde of free wraiths, unleashed one by one from the shielding grip of the star wards. But on the day the last wraith is redeemed, the inflexible terms sealed by Dakar's oath of debt will be forfeit... Against a backdrop in which the Religion of Light has undergone schism, the fanatical True Sect's high priesthood stands consumed by its thwarted ambition: to conquer Havish, the backbone of order that secures the terms of Paravian survival. Now Lord Mayor of Etarra, Lysaer s'Ilessid must fight the pull of the Mistwraith's curse, and battle for sanity to uphold his just ethic. Another young defender will stand at his side, newly sworn by the Sorcerer's auspices. As Arithon's life once again becomes the fulcrum that shifts the game board, Elaira's choice might save or break the unstable future; while at large and answerable to no mortal law, Davien and the dragon that holds his service throw in the wild card no one predicts...
Author: Curtis L. Meinert Publisher: Oxford University Press, USA ISBN: 9780195035681 Category : Clinical trials Languages : en Pages : 502
Book Description
The definitive reference work on clinical trials, this book presents a wealth of detailed, practical information on the design, conduct, and analysis of both single center and multicenter trials. No other book on clinical trials offers as much detail as Meinert does on such issues as samplesize calculation, stratification and randomization, data systems design, consent form development, publication policies, preparation of funding requests, and reporting procedures.
Author: K. Paul Johnson Publisher: State University of New York Press ISBN: 1438407955 Category : Religion Languages : en Pages : 280
Book Description
The author examines the careers of the most distinguished disciples of the Theosophical Masters. He begins by examining the concept of initiation promoted by the Theosophical movement's founders. Each section investigates a separate category of initiates, focusing consecutively on Hindus, Muslims, Bahais, Buddhists, and the Western female occultists. More than just a study of Theosophy, this book explores many related developments in political and religious history. Among the figures it illumines in new ways are Anagarika Dharmapala, Alexandra David-Neel, George Ivanovitch Gurdjieff, and Isabelle Eberhardt. Its approach brings needed objectivity and balance to a topic too long mythologized by cultists and ignored by scholars.
Author: Tristan Vaughan Publisher: John Wiley & Sons ISBN: 3527699147 Category : Medical Languages : en Pages : 726
Book Description
In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
Author: Helena Petrovna Blavatsky Publisher: Philaletheians UK ISBN: Category : Religion Languages : en Pages : 27
Book Description
The first, semi-divine, pure and spiritual Race of Humanity had the “truths of God,” and lived up to them, and their ideals. They preserved them, so long as there was hardly any evil, and hence scarcely a possible abuse of that knowledge and those truths. But evolution and the gradual fall into materiality is also one of the “truths” and also one of the laws of “God.” And as mankind progressed, and became with every generation more of the earth, earthly, the individuality of each temporary Ego began to assert itself. It is personal selfishness that develops and urges man on to abuse of his knowledge and power. And selfishness is a human building, whose windows and doors are ever wide open for every kind of iniquity to enter into man’s soul. Few were the men during the early adolescence of mankind, and fewer still are they now, who feel disposed to put into practice Pope’s forcible declaration that he would tear out his own heart, if it had no better disposition than to love only himself, and laugh at all his neighbours. Hence the necessity of gradually taking away from man the divine knowledge and power, which became with every new human cycle more dangerous as a double-edged weapon, whose evil side was ever threatening one’s neighbour, and whose power for good was lavished freely only upon self. Those few “elect” whose inner natures had remained unaffected by their outward physical growth, thus became in time the sole guardians of the mysteries revealed, passing the knowledge to those most fit to receive it, and keeping it inaccessible to others. Reject this explanation from the Secret Teachings, and the very name of Religion will become synonymous with deception and fraud.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309171148 Category : Medical Languages : en Pages : 221
Book Description
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Author: douard Schur Publisher: SteinerBooks ISBN: 0880109939 Category : Religion Languages : en Pages : 549
Book Description
"You are not expected to complete the work, nor are you permitted to abandon it." --Rabbi Tarfon, Pirke Avot In this remarkable, groundbreaking book, Shulamit Elson writes with eloquence and authority about our soul's journey, our place in the universe, and our relationship to God through prayer. In beautiful and simple words, she shares the ancient teachings and the sacred sounds of the Kabbalah in ways capable of reconnecting us with the Eternal and changing our lives forever. We learn of her journey from the closed world of an Orthodox Jewish family, on a voyage of discovery that took her into a secular life of poetry and travel throughout Europe. Then, faced with personal difficulties and waking visions, she began a path of meditation. Gifts of healing and prophecy followed. Eventually she met her Maggid, the traditional Kabbalistic "answering angel," with whose help she developed a series of meditative "Sound Prayers" using sacred sounds made with the voice. Elson explains the theological, cosmological, and esoteric foundations upon which "Sound Prayer" is based. We are introduced to the ancient wisdom of the Kabbalah, the "Tree of Life," and the structure of the soul in its relationship with God. We learn the true nature of prayer, how it relates to Tikkun Olam ("Repair of the World"), and how "Sound Prayer" relates to different angelic levels of being and truth. This is a practical book that gives individual exercises as well as offering help on meeting specific challenges, including spiritual struggles, feelings of meaninglessness, and harsh self-judgment, as well as illness, fear, and anxiety.
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Author: Janny Wurts
Author: Janny Wurts
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Author: Rudolf Steiner
Author: Curtis L. Meinert
Author: K. Paul Johnson
Author: Tristan Vaughan
Author: Helena Petrovna Blavatsky
Author: Institute of Medicine
Author: douard Schur