Understanding the "Why" Chromosome

Author: Cathy Guisewite
Publisher: Andrews McMeel Publishing
ISBN: 9780836204230
Category : Humor
Languages : en
Pages : 0

Book Description
"My job isn't to revolutionize anything. My job is to give women a sense of relief, to acknowledge what they're struggling with." --Cathy Guisewite Like women around the globe, Cathy has been constantly puzzled by her romantic relationships. From Irving to Simon to Alex, the men in Cathy's life have provided a never-ending source of confusion and amusement ever since the strip began in 1976. "If men's hair falls out," our weary heroine laments, "it's because there's nothing in there for it to hold onto." It's no wonder, then, that cartoonist Cathy Guisewite's Cathy collection should be called Understanding the "Why" Chromosome. In this hilarious book, Cathy outdoes herself in witty revelations about men, food, Mom, and career: Cathy's four basic guilt groups. Cathy epitomizes the highs and lows felt by distaff women throughout the world. In Understanding the "Why" Chromosome, Cathy's found a new challenge: a boyfriend who's a decade younger than she. Fitness fanatic Alex, who's sensitive and not particularly ambitious, introduces Cathy to an entirely new relationship angst, then introduces her to his hip, young mother. Cathy's baffled by the age difference, but is just as stumped when he proposes. "What's wrong with our relationship the way it is now? "she wails when Alex finally pops the question. Throughout her trials and tribulations, Cathy's friends keep her sane. There's happily married Charlene, the office loudspeaker; exhausted Andrea, mother of Zenith and Gus; her well-meaning mom and dad; Cathy's unrealistic boss Mr. Pinkley; and bouncy little Electra, Cathy's canine alter ego. Her frequent and frustrating shopping excursions also give rise to an enormous wave of female recognition "Skip the clothes and just shove a Stairmaster through the curtain," Cathy deadpans. Cathy Guisewite is an enormously talented cartoonist who has won numerous awards for her strip and animated television shows. Her countless fans trust Cathy to constantly express the right blend of humor and observation almost as if she had x-ray vision into the human condition.

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment

Author: Jessica Wapner
Publisher: The Experiment, LLC
ISBN: 1615191658
Category : Health & Fitness
Languages : en
Pages : 345

Book Description
One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Chromosome Biology as a Key to Understand Disease Mechanisms, Genome Architecture and Evolution

Author: Anja Weise
Publisher: Frontiers Media SA
ISBN: 2889666816
Category : Science
Languages : en
Pages : 94

Book Description
This topic has been realized, and is in collaboration with Dr. Constanze Pentzold, Post Doctoral Researcher at the Institute of Human Genetics, University Hospital Jena.

Chromosome Structure and Function

Author: Rudi Appels
Publisher: Springer Science & Business Media
ISBN: 1461310377
Category : Medical
Languages : en
Pages : 336

Book Description
A Historical Perspective on the Study of Chromosome Structure and Function R. Appels Division of Plant Industry CSIRO P.O. Box 1600 A.C.T. AUSTRALIA "Modern physical science gives us no model to explain the re duplication of the gene-string in each cell generation, or to ex plain the production of effective quantities of specific enzymes or other agents by specific genes. The precise pairing and inter change of segments by homologous gene-strings at meiosis also suggest novel physical properties of this form of matter". Stadler (1954) The very strong influence of reductionism in the history of understanding chromosome structure and function is evident in the above quotation from Stadler's 1954 paper, "The gene". Earlyob servations on the constancy of the cytological appearance of chromo somes and their regular behaviour in cell division led to specula tion on their biological importance. As genetics became more refined in the early decades of the 20th century the genes-on-a string model of chromosomes developed and greater emphasis was placed on the further dissection of these structures. As a result, in the 1980's the reductionist approach is reaching a crest as extensive regions of the genetic material are being sequenced.

Understanding Genetics

Author: Norman V. Rothwell
Publisher:
ISBN: 9780683073898
Category : Genetics
Languages : en
Pages : 486

Book Description

Chromosome Botany

Author: Archana Sharma
Publisher: CRC Press
ISBN: 1482279908
Category : Science
Languages : en
Pages : 168

Book Description
The book covers both the basics of plant chromosomes as well as advances such as molecular characteristics, to give the reader an understanding of the chromosome as vehicle of hereditary transmission. It is meant for all levels of students in genetics, evolution, and biodiversity.

Genetic Translocations and Other Chromosome Aberrations

Author: Guy T. Leyden
Publisher: Nova Publishers
ISBN: 9781604563443
Category : Chromosome abnormalities
Languages : en
Pages : 314

Book Description
Chromosomal aberrations are disruptions in the normal chromosomal content of a cell, and are a major cause of genetic conditions in humans, such as Down syndrome. Some chromosome abnormalities do not cause disease in carriers, such as translocations, or chromosomal inversions, although they may lead to a higher chance of having a child with a chromosome disorder. Abnormal numbers of chromosomes or chromosome sets, aneuploidy, may be lethal or give rise to genetic disorders. Genetic counseling is offered for families that may carry a chromosome rearrangement. This book offers leading-edge research from around the world.

Chromosome Structure and Aberrations

Author: Tariq Ahmad Bhat
Publisher: Springer
ISBN: 8132236734
Category : Medical
Languages : en
Pages : 377

Book Description
This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.

Understanding How Science Explains the World

Author: Kevin McCain
Publisher: Cambridge University Press
ISBN: 1009002589
Category : Science
Languages : en
Pages : 143

Book Description
All people desire to know. We want to not only know what has happened, but also why it happened, how it happened, whether it will happen again, whether it can be made to happen or not happen, and so on. In short, what we want are explanations. Asking and answering explanatory questions lies at the very heart of scientific practice. The primary aim of this book is to help readers understand how science explains the world. This book explores the nature and contours of scientific explanation, how such explanations are evaluated, as well as how they lead to knowledge and understanding. As well as providing an introduction to scientific explanation, it also tackles misconceptions and misunderstandings, while remaining accessible to a general audience with little or no prior philosophical training.

Genetics For Dummies

Author: Tara Rodden Robinson
Publisher: John Wiley & Sons
ISBN: 1119633036
Category : Science
Languages : en
Pages : 403

Book Description
Your no-nonsense guide to genetics With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry. This new edition of Genetics For Dummies serves as a perfect course supplement for students pursuing degrees in the sciences. It also provides science-lovers of all skill levels with easy-to-follow and easy-to-understand information about this exciting and constantly evolving field. This edition includes recent developments and applications in the field of genetics, such as: Whole-genome and whole-exome sequencing Precision medicine and pharmacogenetics Direct-to-consumer genetic testing for health risks Ancestry testing Featuring information on some of the hottest topics in genetics right now, this book makes it easier than ever to wrap your head around this fascinating subject.