Acquiring Genomes

Author: Lynn Margulis
Publisher: Basic Books
ISBN: 0786722606
Category : Science
Languages : en
Pages : 262

Book Description
In this groundbreaking book, Lynn Margulis and Dorion Sagan present an answer to one of the enduring mysteries of evolution -- the source of inherited variation that gives rise to new species. Random genetic mutation, long believed to be the main source of variation, is only a marginal factor. As the authors demonstrate in this book, the more important source of speciation, by far, is the acquisition of new genomes by symbiotic merger. The result of thirty years of delving into a vast, mostly arcane literature, this is the first book to go beyond -- and reveal the severe limitations of -- the "Modern Synthesis" that has dominated evolutionary biology for almost three generations. Lynn Margulis, whom E. O. Wilson called "one of the most successful synthetic thinkers in modern biology," and her co-author Dorion Sagan have written a comprehensive and scientifically supported presentation of a theory that directly challenges the assumptions we hold about the variety of the living world.

The Microbial State

Author: Stefanie R. Fishel
Publisher: U of Minnesota Press
ISBN: 1452955484
Category : Political Science
Languages : en
Pages : 182

Book Description
For three centuries, concepts of the state have been animated by one of the most powerful metaphors in politics: the body politic, a claustrophobic and bounded image of sovereignty. Climate change, neoliberalism, mass migration, and other aspects of the late Anthropocene have increasingly revealed the limitations of this metaphor. Just as the human body is not whole and separate from other bodies—comprising microbes, bacteria, water, and radioactive isotopes—Stefanie R. Fishel argues that the body politic of the state exists in dense entanglement with other communities and forms of life. Drawing on insights from continental philosophy, science and technology studies, and international relations theory, this path-breaking book critiques the concept of the body politic on the grounds of its very materiality. Fishel both redefines and extends the metaphor of the body politic and its role in understanding an increasingly posthuman, globalized world politics. By conceiving of bodies and states as lively vessels, living harmoniously with multiplicity and the biosphere, she argues that a radical shift in metaphors can challenge a politics based on fear to open new forms of global political practice and community. Reframing the concept of the body politic to accommodate greater levels of complexity, Fishel suggests, will result in new configurations for the political and social organization necessary to build a world in which the planet’s inhabitants do not merely live but actively thrive.

Symbiotic Planet

Author: Lynn Margulis
Publisher: Basic Books
ISBN: 078672448X
Category : Science
Languages : en
Pages : 158

Book Description
Although Charles Darwin's theory of evolution laid the foundations of modern biology, it did not tell the whole story. Most remarkably, The Origin of Species said very little about, of all things, the origins of species. Darwin and his modern successors have shown very convincingly how inherited variations are naturally selected, but they leave unanswered how variant organisms come to be in the first place. In Symbiotic Planet, renowned scientist Lynn Margulis shows that symbiosis, which simply means members of different species living in physical contact with each other, is crucial to the origins of evolutionary novelty. Ranging from bacteria, the smallest kinds of life, to the largest -- the living Earth itself -- Margulis explains the symbiotic origins of many of evolution's most important innovations. The very cells we're made of started as symbiotic unions of different kinds of bacteria. Sex -- and its inevitable corollary, death -- arose when failed attempts at cannibalism resulted in seasonally repeated mergers of some of our tiniest ancestors. Dry land became forested only after symbioses of algae and fungi evolved into plants. Since all living things are bathed by the same waters and atmosphere, all the inhabitants of Earth belong to a symbiotic union. Gaia, the finely tuned largest ecosystem of the Earth's surface, is just symbiosis as seen from space. Along the way, Margulis describes her initiation into the world of science and the early steps in the present revolution in evolutionary biology; the importance of species classification for how we think about the living world; and the way "academic apartheid" can block scientific advancement. Written with enthusiasm and authority, this is a book that could change the way you view our living Earth.

Microcosmos

Author: Lynn Margulis
Publisher: Univ of California Press
ISBN: 0520340515
Category : Science
Languages : en
Pages : 304

Book Description
"Microcosmos is nothing less than the saga of the life of the planet. Lynn Margulis and Dorion Sagan have put it all together, literally, in this extraordinary book, which is unlike any treatment of evolution for a general readership that I have encountered before. A fascinating account that we humans should be studying now for clues to our own survival."—From the Foreword by Dr. Lewis Thomas Microcosmos brings together the remarkable discoveries of microbiology in the later decades of the 20th century and the pioneering research of Dr. Margulis to create a vivid new picture of the world that is crucial to our understanding of the future of the planet. Addressed to general readers, the book provides a beautifully written view of evolution as a process based on interdependency and their interconnectedness of all life on the planet.

Genomes

Author: T.A. Brown
Publisher: Garland Science
ISBN: 1136969969
Category : Science
Languages : en
Pages : 736

Book Description
Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, Genomes 3 is the latest edition of this pioneering textbook. Newly updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics. Following extensive reviewing, the new edition has been significantly restructured. The single chapter on genome anatomies has been expanded into three chapters to incorporate the latest sequencing achievements. An additional chapter on understanding genome expression has also been included, while the chapters on studying genomes have been brought to the front of the book to align it more closely to the practical reality of molecular genetics tuition. The end-of-chapter exercises have been overhauled and extended to give students and lecturers a much wider range of tests and challenges. Multiple choice questions have been included for the first time and an innovative figure test has been introduced to test readers' visual understanding.

The Evolution of the Genome

Author: T. Ryan Gregory
Publisher: Elsevier
ISBN: 0080470521
Category : Science
Languages : en
Pages : 768

Book Description
The Evolution of the Genome provides a much needed overview of genomic study through clear, detailed, expert-authored discussions of the key areas in genome biology. This includes the evolution of genome size, genomic parasites, gene and ancient genome duplications, polypoidy, comparative genomics, and the implications of these genome-level phenomena for evolutionary theory. In addition to reviewing the current state of knowledge of these fields in an accessible way, the various chapters also provide historical and conceptual background information, highlight the ways in which the critical questions are actually being studied, indicate some important areas for future research, and build bridges across traditional professional and taxonomic boundaries. The Evolution of the Genome will serve as a critical resource for graduate students, postdoctoral fellows, and established scientists alike who are interested in the issue of genome evolution in the broadest sense. - Provides detailed, clearly written chapters authored by leading researchers in their respective fields - Presents a much-needed overview of the historical and theoretical context of the various areas of genomic study - Creates important links between topics in order to promote integration across subdisciplines, including descriptions of how each subject is actually studied - Provides information specifically designed to be accessible to established researchers, postdoctoral fellows, and graduate students alike

Dazzle Gradually

Author: Lynn Margulis
Publisher: Chelsea Green Publishing
ISBN: 1603581367
Category : Science
Languages : en
Pages : 282

Book Description
At the crossroads of philosophy and science, the sometimes-dry topics of evolution and ecology come alive in this new collection of essays--many never before anthologized. Learn how technology may be a sort of second nature, how the systemic human fungus Candida albicans can lead to cravings for carrot cake and beer, how the presence of life may be why there's water on Earth, and many other fascinating facts. The essay "Metametazoa" presents perspectives on biology in a philosophical context, demonstrating how the intellectual librarian, pornographer, and political agitator Georges Bataille was influenced by Russian mineralogist Vladimir Vernadsky and how this led to his notion of the absence of meaning in the face of the sun--which later influenced Jacques Derrida, thereby establishing a causal chain of influence from the hard sciences to topics as abstract as deconstruction and post-modernism. In "Spirochetes Awake" the bizarre connection between syphilis and genius in the life of Friedrich Nietzsche is traced. The astonishing similarities of the Acquired-Immune-Deficiency-Syndrome symptoms with those of chronic spirochete infection, it is argued, contrast sharply with the lack of evidence that "HIV is the cause of AIDS". Throughout these readings we are dazzled by the intimacy and necessity of relationships between us and our other planetmates. In our ignorance as "civilized" people we dismiss, disdain, and deny our kinship with the only productive life forms that sustain this living planet.

Genomes 4

Author: T. A. Brown
Publisher: Garland Science
ISBN: 1351851292
Category : Science
Languages : en
Pages : 520

Book Description
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.

Computational Methods For Understanding Bacterial And Archaeal Genomes

Author: Ying Xu
Publisher: World Scientific
ISBN: 1908979011
Category : Science
Languages : en
Pages : 494

Book Description
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses./a

Lynn Margulis

Author: Dorion Sagan
Publisher: Chelsea Green Publishing
ISBN: 1603584471
Category : Biography & Autobiography
Languages : en
Pages : 219

Book Description
Tireless, controversial, and hugely inspirational to those who knew her or encountered her work, Lynn Margulis was a scientist whose intellectual energy and interests knew no bounds. Best known for her work on the origins of eukaryotic cells, the Gaia hypothesis, and symbiogenesis as a driving force in evolution, her work has forever changed the way we understand life on Earth. When Margulis passed away in 2011, she left behind a groundbreaking scientific legacy that spanned decades. In this collection, Dorion Sagan, Margulis's son and longtime collaborator, gathers together the voices of friends and colleagues to remark on her life and legacy, in essays that cover her early collaboration with James Lovelock, her fearless face-off with Richard Dawkins during the so-called "Battle of Balliol" at Oxford, the intrepid application of her scientific mind to the insistence that 9/11 was a false-flag operation, her affinity for Emily Dickinson, and more. Margulis was elected to the National Academy of Sciences in 1983, received the prestigious National Medal of Science in 1999, and her papers are permanently archived at the Library of Congress. Less than a month before her untimely death, Margulis was named one of the twenty most influential scientists alive - one of only two women on this list, which include such scientists as Stephen Hawking, James Watson, and Jane Goodall.