Small Doses

Small Doses PDF Author: Amanda Seales
Publisher: Abrams
ISBN: 168335494X
Category : Humor
Languages : en
Pages : 435

Book Description
This “one-of-a-kind read” offers insightful essays, poignant life advice, and pithy pearls of wisdom from the comedian and star of HBO’s Insecure (Entertainment Weekly). Anyone who has seen Amanda Seales’s acclaimed stand-up special I Be Knowin, her long-running TV series Insecure, or her groundbreaking gameshow Smart Funny & Black, knows that this woman is a force of nature. In both life and career, she has fearlessly and passionately charted her own course. Now she’s bringing her life’s lessons and laughs to the page with her signature blend of academic intellectualism, Black American colloquialisms, and pop culture fanaticism. This volume of essays, axioms, original illustrations, and photos provides Seales’s trademark “self-help from the hip” style of commentary, fueled by ideology formed from her own victories, struggles, research, mistakes, risks, and pay-offs. Unapologetic, fiercely funny, and searingly honest, Small Doses engages, empowers, and enlightens readers on how to find their truths while still finding the funny!

The Truth in Small Doses

The Truth in Small Doses PDF Author: Clifton Leaf
Publisher: Simon and Schuster
ISBN: 1476739986
Category : History
Languages : en
Pages : 513

Book Description
A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.

Management in Small Doses

Management in Small Doses PDF Author: Russell L. Ackoff
Publisher:
ISBN:
Category : Business & Economics
Languages : en
Pages : 232

Book Description
Ackoff gives the reader 52 small doses of sound management thinking, delivered with characteristic Ackoff wit, humor and clarity.

Statistics in Small Doses

Statistics in Small Doses PDF Author: Win M. Castle
Publisher:
ISBN: 9780443045424
Category : Biometry
Languages : en
Pages : 0

Book Description
Many medical and pharmaceutical workers have very little knowledge of statistics. Yet statistics is one of the tools must commonly used in their field. This book aims to give the reader a clear understanding of statistics, particularly in a medical context.The book has been carefully structured to make it easy to use and to learn from. The numerical examples used are simple, to ensure the reader grasps quickly the underlying principles, and the first part of the book is particularly easy reading to encourage the reader initially. The main part of the book dispenses in formation in small doses called 'frames' with questions and answers designed to continously test the reader's grasp of the subject matter. This makes the book particularly useful for self-testing - a powerful way to learn. Moreover, many of the answers feature further explanation or comment to give background to the point being made.As a whole, the book is meant to be read from start to finish (not 'dipped into') so that each point leads on logically, building up the reader's knowledge sequentially. However to cement that knowledge and help revision, each chapter ends with revision summaries covering fully the chapter

The Truth in Small Doses

The Truth in Small Doses PDF Author: Clifton Leaf
Publisher: Simon and Schuster
ISBN: 1476739994
Category : History
Languages : en
Pages : 512

Book Description
A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.

Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence

Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence PDF Author: World Health Organization. Department of Mental Health and Substance Abuse
Publisher: World Health Organization
ISBN: 9241547545
Category : Medical
Languages : en
Pages : 133

Book Description
"These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv

Low Dose Radiation

Low Dose Radiation PDF Author: Antone L. Brooks
Publisher:
ISBN: 9780874223545
Category : Science
Languages : en
Pages : 0

Book Description
Chief Scientist Dr. Antone Brooks and his Low Dose Radiation Research Program team redefined the field, applying advances in instrumentation and molecular biology from the Human Genome Project and developing new technologies to examine cellular responses. Their findings were startling. At low doses, biological reactions are unique and often unrelated to those that occur at high doses. The influential linear-no-threshold model--which predicted that damage from acute exposures can be extrapolated linearly to low dose exposures--was flawed. Small doses of radiation can have an adaptive protective effect. "Hit theory," the idea that radiation only affected cells it directly traversed, yielded to "bystander theory," which hypothesizes that cells communicate with each other and a dose to one affects others surrounding it. Low Dose Radiation describes the program's development, the scientists who made it viable, and the fundamental results, highlighting lessons learned during its lifespan.

Small Clinical Trials

Small Clinical Trials PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309171148
Category : Medical
Languages : en
Pages : 221

Book Description
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
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