Bioinformatics and Functional Genomics

Author: Jonathan Pevsner
Publisher: John Wiley & Sons
ISBN: 0471459178
Category : Science
Languages : en
Pages : 792

Book Description
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.

Genomics and Bioinformatics

Author: Tore Samuelsson
Publisher: Cambridge University Press
ISBN: 1107378338
Category : Science
Languages : en
Pages : 357

Book Description
With the arrival of genomics and genome sequencing projects, biology has been transformed into an incredibly data-rich science. The vast amount of information generated has made computational analysis critical and has increased demand for skilled bioinformaticians. Designed for biologists without previous programming experience, this textbook provides a hands-on introduction to Unix, Perl and other tools used in sequence bioinformatics. Relevant biological topics are used throughout the book and are combined with practical bioinformatics examples, leading students through the process from biological problem to computational solution. All of the Perl scripts, sequence and database files used in the book are available for download at the accompanying website, allowing the reader to easily follow each example using their own computer. Programming examples are kept at an introductory level, avoiding complex mathematics that students often find daunting. The book demonstrates that even simple programs can provide powerful solutions to many complex bioinformatics problems.

Bioinformatics and Human Genomics Research

Author: Diego A. Forero
Publisher: CRC Press
ISBN: 1000405672
Category : Science
Languages : en
Pages : 374

Book Description
Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

Essentials of Genomics and Bioinformatics

Author: Christoph W. Sensen
Publisher: John Wiley & Sons
ISBN: 3527612653
Category : Science
Languages : de
Pages : 442

Book Description
Provides an overview of the rapidly evolving field of genomics with coverage of nucleic acid technologies, proteomics and bioinformatics. It includes chapters on applications in human health, agriculture and comparative genomics and also contains two chapters on the legal and ethical issues of genomics, a topic that is becoming increasingly important as genomics moves out of the laboratory into practical applications.

Bioinformatics, Genomics, and Proteomics

Author: Ann Finney Batiza
Publisher: Infobase Publishing
ISBN: 1438121563
Category : Computers
Languages : en
Pages : 223

Book Description
Get "the big picture" of how biotechnology works.

Bioinformatics for Beginners

Author: Supratim Choudhuri
Publisher: Elsevier
ISBN: 0124105106
Category : Science
Languages : en
Pages : 238

Book Description
Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration

Computing for Comparative Microbial Genomics

Author: David Wayne Ussery
Publisher: Springer Science & Business Media
ISBN: 1848002548
Category : Science
Languages : en
Pages : 272

Book Description
Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.

Genomics and Bioinformatics

Author: Tore Samuelsson
Publisher: Cambridge University Press
ISBN: 1107008565
Category : Computers
Languages : en
Pages : 357

Book Description
A hands-on introduction to Unix, Perl and other bioinformatics tools using relevant and interesting molecular biology problems.

Bioinformatics for High Throughput Sequencing

Author: Naiara Rodríguez-Ezpeleta
Publisher: Springer Science & Business Media
ISBN: 1461407826
Category : Science
Languages : en
Pages : 258

Book Description
Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.

Concepts in Bioinformatics and Genomics

Author: Jamil Momand
Publisher:
ISBN: 9780190610548
Category : Bioinformatics
Languages : en
Pages : 0

Book Description
Review of molecular biology 1 -- Information organization and sequence databases -- Molecular evolution -- Substitution matrices -- Pairwise sequence alignment-- Basic local alignment sequence tool and multiple sequence alignment -- Protein structure prediction -- Phylogenetics -- Genomics -- Transcript and protein expression analysis -- Basic probability -- Advanced probability for bioinformatics applications -- Programming basics and applications to bioinformatics -- Developing a bioinformatics tool