Understanding the "Why" Chromosome

Understanding the Author: Cathy Guisewite
Publisher: Andrews McMeel Publishing
ISBN: 9780836204230
Category : Humor
Languages : en
Pages : 0

Book Description
"My job isn't to revolutionize anything. My job is to give women a sense of relief, to acknowledge what they're struggling with." --Cathy Guisewite Like women around the globe, Cathy has been constantly puzzled by her romantic relationships. From Irving to Simon to Alex, the men in Cathy's life have provided a never-ending source of confusion and amusement ever since the strip began in 1976. "If men's hair falls out," our weary heroine laments, "it's because there's nothing in there for it to hold onto." It's no wonder, then, that cartoonist Cathy Guisewite's Cathy collection should be called Understanding the "Why" Chromosome. In this hilarious book, Cathy outdoes herself in witty revelations about men, food, Mom, and career: Cathy's four basic guilt groups. Cathy epitomizes the highs and lows felt by distaff women throughout the world. In Understanding the "Why" Chromosome, Cathy's found a new challenge: a boyfriend who's a decade younger than she. Fitness fanatic Alex, who's sensitive and not particularly ambitious, introduces Cathy to an entirely new relationship angst, then introduces her to his hip, young mother. Cathy's baffled by the age difference, but is just as stumped when he proposes. "What's wrong with our relationship the way it is now? "she wails when Alex finally pops the question. Throughout her trials and tribulations, Cathy's friends keep her sane. There's happily married Charlene, the office loudspeaker; exhausted Andrea, mother of Zenith and Gus; her well-meaning mom and dad; Cathy's unrealistic boss Mr. Pinkley; and bouncy little Electra, Cathy's canine alter ego. Her frequent and frustrating shopping excursions also give rise to an enormous wave of female recognition "Skip the clothes and just shove a Stairmaster through the curtain," Cathy deadpans. Cathy Guisewite is an enormously talented cartoonist who has won numerous awards for her strip and animated television shows. Her countless fans trust Cathy to constantly express the right blend of humor and observation almost as if she had x-ray vision into the human condition.

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment PDF Author: Jessica Wapner
Publisher: The Experiment, LLC
ISBN: 1615191658
Category : Health & Fitness
Languages : en
Pages : 345

Book Description
One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Understanding Genetics

Understanding Genetics PDF Author: Rajiv Tyagi
Publisher: Discovery Publishing House
ISBN: 9788183564588
Category : Cytogenetics
Languages : en
Pages : 352

Book Description

Chromosome 6

Chromosome 6 PDF Author: Robin Cook
Publisher: Penguin
ISBN: 9780425161241
Category : Fiction
Languages : en
Pages : 484

Book Description
“Master of the medical thriller.”—The New York Times In his most prophetic thriller yet, Robin Cook goes behind the headlines on cloning and genetic manipulation, blending fact with fiction in this terrifying bestseller. In the jungles of equatorial Africa, a biotechnology giant has taken transplant surgery and animal research to a new level—where one mistake could bridge the evolutionary gap between man and ape and forever change the genetic map of our existence. Meanwhile, in New York City, Jack Stapleton and Laurie Montgomery are working on a seemingly unrelated murder of a mobster, only to find some very odd things once their victim is on the autopsy table...

Genes, Chromosomes, and Disease

Genes, Chromosomes, and Disease PDF Author: Nicholas Wright Gillham
Publisher: FT Press
ISBN: 0132623242
Category : Medical
Languages : en
Pages : 353

Book Description
This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

Genome

Genome PDF Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0062253468
Category : Science
Languages : en
Pages : 370

Book Description
“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Cytogenomics

Cytogenomics PDF Author: Thomas Liehr
Publisher: Academic Press
ISBN: 0128235802
Category : Science
Languages : en
Pages : 430

Book Description
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book's second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. - Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies - Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease - Features chapter contributions from international leaders in the field

Understanding DNA

Understanding DNA PDF Author: Chris R. Calladine
Publisher: Academic Press
ISBN: 0080572529
Category : Science
Languages : en
Pages : 349

Book Description
The Second Edition of Understanding DNA has been entirely revised and updated, and expanded by more than 50% to cover new advances. The book explains step-by-step how DNA forms specific structures, the nature of these structures, and how they fundamentally affect the biological processes of transcription and replication.The functional properties of any molecule are directly related to and affected by its structure; this is especially true for DNA, the molecule that carries the code for all life on earth. Written in a clear, concise, and at times lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry, and genetics students, for newcomers to the field from such areas as physics or chemistry, and for even the most seasoned researchers who really want to understand DNA.Key Features* New edition, expanded by more than 50%* Completely revised and updated* Includes many additional and updated references* Summarizes the recent studies of DNA in disease and medicine* Contains more than 110 illustrations, some in full color* Describes the basic units of DNA and how these form the double helix* Characterizes the various types of DNA double helix that have been found* Explains how and why DNA twists and curves* Discusses the mechanisms of DNA supercoiling* Summarizes the assembly of DNA and proteins into chromosomes* Outlines the methods used to study DNA structureDescribes the latest work on protein-DNA complexes* Contains simple exercises and further reading at the end of each chapter

Genetics For Dummies

Genetics For Dummies PDF Author: Tara Rodden Robinson
Publisher: John Wiley & Sons
ISBN: 1119633036
Category : Science
Languages : en
Pages : 403

Book Description
Your no-nonsense guide to genetics With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry. This new edition of Genetics For Dummies serves as a perfect course supplement for students pursuing degrees in the sciences. It also provides science-lovers of all skill levels with easy-to-follow and easy-to-understand information about this exciting and constantly evolving field. This edition includes recent developments and applications in the field of genetics, such as: Whole-genome and whole-exome sequencing Precision medicine and pharmacogenetics Direct-to-consumer genetic testing for health risks Ancestry testing Featuring information on some of the hottest topics in genetics right now, this book makes it easier than ever to wrap your head around this fascinating subject.
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